This graph is a representation of the cell nucleus with its DNA included. The yellow segment indicates the presence of an oncogene. An oncogene, is an abnormal, mutated gene, encoding for a protein that will cause uncontrolled cell growth and proliferation.

This graph shows the amplification of, or uncontrolled replication, of an oncogene.
As a result, there will be an increase in oncogenic mRNA and also, in the growth factors encoded within.

The nucleus is shown within the cell and, abnormal levels of oncogenic mRNA are shown in in the cytoplasm. The high levels of oncogenic mRNA, will be translated in an increased synthesis of abnormal growth factors, which willl cause uncontrolled cell growth and proliferation.

To evaluate whether if GC100 can induce a reduction, in the amount of oncogenic mRNA, we conducted a series of experiments, in which GC100 was added to the cell culture of various glioblastoma and neuroblastoma cancer cell lines. 

Our results show that the introduction, of 1mg of GC100 in both of the above lines of cancer cell cultures, were able to produce a dramatic reduction in the synthesis of oncogenic mRNA.

These results were compared with the oncogenic mRNA in the control cell culture, in which no GC100 was incorporated. Exposure to GC100,  produced a gradual inhibition in the synthesis of oncogenoic mRNA. A maximuma inhibition, (80%) was observed after 48 hours exposure to GC100.  

View laboratory test
for mRNA